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Free CSPT Practice Questions

10 free, exam-style Certified Compounded Sterile Preparation Technician (CSPT) practice questions with answers and explanations. No signup required. Work through them below, then take the full free CSPT practice test to study every exam domain.

These 10 free CSPT questions are organized by exam domain, so you can see how each part of the Certified Compounded Sterile Preparation Technician blueprint is tested. Reveal the answer and explanation under each question.

Domain 1: Medications and Components 17% of exam

Question 1

Which statement BEST describes the beyond-use date (BUD) of a compounded sterile preparation?

  1. It is the same as the manufacturer's expiration date for the active ingredient
  2. It is set by the prescriber according to the planned duration of the therapy
  3. It is based only on the chemical stability of the active drug in solution
  4. It is the date or time after which the CSP must not be used or stored
Show answer & explanation

Correct answer: D - It is the date or time after which the CSP must not be used or stored

Domain 2: Facilities and Equipment 22% of exam

Question 2

A technician must compound a hazardous antineoplastic drug. Which primary engineering control is appropriate?

  1. Horizontal laminar airflow workbench (LAFW)
  2. Compounding aseptic isolator (CAI), non-containment
  3. Open clean bench with HEPA-filtered horizontal air
  4. Class II biological safety cabinet (BSC)
Show answer & explanation

Correct answer: D - Class II biological safety cabinet (BSC)

Question 3

A buffer room that houses the primary engineering control for Category 2 CSPs must meet which minimum air cleanliness classification?

  1. ISO Class 5
  2. ISO Class 7
  3. ISO Class 8
  4. ISO Class 9
Show answer & explanation

Correct answer: B - ISO Class 7

Domain 3: Sterile Compounding Procedures 53% of exam

Question 4

Under the revised USP <797>, which factor determines whether a compounded sterile preparation is classified as Category 1, Category 2, or Category 3?

  1. The microbial risk level it is assigned: low, medium, or high contamination risk
  2. The number of sterile ingredients combined in the final preparation
  3. The route by which the finished preparation will be administered to the patient
  4. The conditions under which it is compounded and the testing performed on it
Show answer & explanation

Correct answer: D - The conditions under which it is compounded and the testing performed on it

Question 5

A dopamine infusion is ordered at 5 mcg/kg/min for a 70 kg patient. The bag contains 400 mg in 250 mL. What is the infusion rate in mL/hr? (Round to the nearest whole number.)

  1. 13 mL/hr
  2. 5 mL/hr
  3. 21 mL/hr
  4. 33 mL/hr
Show answer & explanation

Correct answer: A - 13 mL/hr

Question 6

Sterile 70% isopropyl alcohol is the standard disinfectant for critical sites and gloved hands, but it is NOT effective against:

  1. Gram-positive vegetative bacteria
  2. Gram-negative vegetative bacteria
  3. Vegetative fungal (mold) cells
  4. Bacterial spores
Show answer & explanation

Correct answer: D - Bacterial spores

Question 7

While compounding in a horizontal laminar airflow workbench, a technician places a stack of supplies between the HEPA filter and an open vial. What is the MOST significant consequence?

  1. The buffer room air changes per hour drop for the rest of the shift
  2. The blocked supplies are sterilized by the first air passing over them
  3. First air is interrupted and the critical site is contaminated
  4. The workbench ISO classification is permanently downgraded by one level
Show answer & explanation

Correct answer: C - First air is interrupted and the critical site is contaminated

Question 8

Personnel who compound Category 3 CSPs must complete media-fill testing and gloved fingertip sampling at a minimum frequency of:

  1. At least every 3 months
  2. At least every 6 months
  3. At least every 12 months
  4. Only once, before initial compounding
Show answer & explanation

Correct answer: A - At least every 3 months

Question 9

When compounding a parenteral nutrition admixture, which practice MOST reduces the risk of calcium-phosphate precipitation?

  1. Use the most concentrated calcium and phosphate salts that are available
  2. Add calcium and phosphate one right after the other with nothing between
  3. Add phosphate early and calcium last, with adequate dilution and mixing
  4. Add both the calcium and phosphate salts after the lipid emulsion is in
Show answer & explanation

Correct answer: C - Add phosphate early and calcium last, with adequate dilution and mixing

Domain 4: Handling, Packaging, Storage, and Disposal 8% of exam

Question 10

Which practice is required when transporting a finished hazardous-drug CSP within the facility?

  1. Send it through the pneumatic tube system to save time
  2. Transport it in a sealed, labeled, leak-proof container
  3. Place it loose on a standard medication delivery cart
  4. Remove the hazardous-drug warning label to avoid alarming staff
Show answer & explanation

Correct answer: B - Transport it in a sealed, labeled, leak-proof container

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